Performance and quality analysis of convolution-based volume illumination

Convolution-based techniques for volume rendering are among the fastest in the on-the-fly volumetric illumination category. Such methods, however, are still considerably slower than conventional local illumination techniques. In this paper we describe how to adapt two commonly used strategies for reducing aliasing artifacts, namely pre-integration and supersampling, to such techniques. These strategies can help reduce the sampling rate of the lighting information (thus the number of convolutions), bringing considerable performance benefits. We present a comparative analysis of their effectiveness in offering performance improvements. We also analyze the (negligible) differences they introduce when comparing their output to the reference method. These strategies can be highly beneficial in setups where direct volume rendering of continuously streaming data is desired and continuous recomputation of full lighting information is too expensive, or where memory constraints make it preferable not to keep additional precomputed volumetric data in memory. In such situations these strategies make single pass, convolution-based volumetric illumination models viable for a broader range of applications, and this paper provides practical guidelines for using and tuning such strategies to specific use cases

Interactive Visual Analysis of Heterogeneous Cohort Study Data

Cohort studies in medicine are conducted to enable the study of medical hypotheses in large samples. Often, a large amount of heterogeneous data is acquired from many subjects. The analysis is usually hypothesis-driven, i.e., a specific subset of such data is studied to confirm or reject specific hypotheses. In this paper, we demonstrate how we enable the interactive visual exploration and analysis of such data, helping with the generation of new hypotheses and contributing to the process of validating them. We propose a data-cube based model which handles partially overlapping data subsets during the interactive visualization. This model enables seamless integration of the heterogeneous data, as well as linking spatial and non-spatial views on these data. We implemented this model in an application prototype, and used it to analyze data acquired in the context of a cohort study on cognitive aging. We present case-study analyses of selected aspects of brain connectivity by using the prototype implementation of the presented model, to demonstrate its potential and flexibility

The indirect effect of cognitive reserve on the relationship between age and cognition in pathological ageing: A cross-sectional retrospective study in an unselected and consecutively enrolled sample

Cognitive reserve (CR) allows individuals to maintain cognitive functionality even in the presence of pathologies. The compensation hypothesis suggests that CR plays an indirect role between age and cognitive decline, contrasting the negative effect of ageing on cognition. We test this hypothesis in an unselected and consecutively enrolled sample of memory clinic attendees (n = 134) who completed the CR Index questionnaire and three neuropsychological tests assessing global cognition (MMSE, FAB, CDT). Participants were divided into two groups based on standard diagnostic criteria (DSM-5): those who were cognitively impaired (n = 92) and those who were preserved (n = 42). A principal component analysis was used to extract a composite measure of global cognitive functioning from the three neuropsychological tests, and mediation analysis was used to examine the relationship between CR, age and global cognitive functioning in the two groups. Results revealed that: (i) age had a significant direct negative effect on the global cognitive score in both groups; (ii) the three socio-behavioural proxies of CR together suppress the direct negative relationship between age and global cognitive score in cognitively impaired patients but not in cognitively preserved participants. This study confirms the association between CR, age and cognition and allows us to validate its role in a population with cognitive impairment and extend findings to a low-to-middle educated population. These results hold important implications for public health and wellness promotion, emphasising the beneficial role of maintaining healthy and active physical, cognitive and social lifestyles

Performance and quality analysis of convolution-based volume illumination

Convolution-based techniques for volume rendering are among the fastest in the on-the-fly volumetric illumination category. Such methods, however, are still considerably slower than conventional local illumination techniques. In this paper we describe how to adapt two commonly used strategies for reducing aliasing artifacts, namely pre-integration and supersampling, to such techniques. These strategies can help reduce the sampling rate of the lighting information (thus the number of convolutions), bringing considerable performance benefits. We present a comparative analysis of their effectiveness in offering performance improvements. We also analyze the (negligible) differences they introduce when comparing their output to the reference method. These strategies can be highly beneficial in setups where direct volume rendering of continuously streaming data is desired and continuous recomputation of full lighting information is too expensive, or where memory constraints make it preferable not to keep additional precomputed volumetric data in memory. In such situations these strategies make single pass, convolution-based volumetric illumination models viable for a broader range of applications, and this paper provides practical guidelines for using and tuning such strategies to specific use cases

Persistence of the cultural landscape in Campania (Southern Italy) before the AD 472 Vesuvius eruption: archaeoenvironmental data

Cultural landscape in late Antiquity at the northern slope of Vesuvius. ► Charcoal analysis, 14C dating and chemical analysis of organic residues. ► Active economic system in late Antiquity with a remarkable agrarian landscape and wine production. ► The most ancient evidence of chestnut silviculture for wood

Accuracy of ultrasonography in the diagnosis of acute appendicitis in adult patients: review of the literature

Background: Ultrasound is a widely used technique in the diagnosis of acute appendicitis; nevertheless, its utilization still remains controversial. Methods: The accuracy of the Ultrasound technique in the diagnosis of acute appendicitis in the adult patient, as shown in the literature, was searched for. Results: The gold standard for the diagnosis of appendicitis still remains pathologic confirmation after appendectomy. In the published literature, graded-compression Ultrasound has shown an extremely variable diagnostic accuracy in the diagnosis of acute appendicitis (sensitivity range from 44% to 100%; specificity range from 47% to 99% ). This is due to many reasons, including lack of operator skill, increased bowel gas content, obesity, anatomic variants, and limitations to explore patients with previuos laparotomies. Conclusions: Graded-compression Ultrasound still remains our first-line method in patients referred with clinically suspected acute appendicitis: nevertheless, due to variable diagnostic accuracy, individual skill is requested not only to perform a successful exam, but also in order to triage those equivocal cases that, subsequently, will have to undergo assessment by means of Computed Tomography